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There are a lot of images of the FTDI out there that show "chip up connector down" but look at the spec sheet. The view of the connector is from the side of that connector and it's easy to get this confused and plug it in upside down. The one I got does not have clearly labeled pins.
Once this was figured out it worked. Tested with a Win10 system using Arduino IDE and also tested with a PineBook Pine64-powered laptop also running Arduino IDE.
The board worked fine, and yes, you need to watch the orientation on connecting to the destination board. My problem is the USB connector peeled up and all the solder joints failed. Think maybe the reflow temp was to low or short. I would reinforce this connector with epoxy if you want to potentially prevent this failure mode. At $15, this is 2X the price of what is on Ebay, which is why I am only giving it 2 stars.